Squeaky clean mice could be ruining research

Masopust began thinking about the cleanliness problem in our labs more than a decade ago. He was struck by how much the immune make-up of lab mice differs from that of humans. At the time, many researchers blamed the differences on genetics, but Masopust suspected that lab mice are different in part because of where they live. “Is this a mouse issue,” he wondered, “or is this really just a lab-mouse issue?”

 

 

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